We have to stop this nonsense that we're going to somehow change the world with one project.”.

The Singapore API plant is the 2024 FOYA Category Winner for Operations, Project Execution.This is thanks to the whole project team's successful delivery of a large and complex project ahead of schedule and under budget during a global pandemic.. GSK Parma Attachment Inhibitor: meeting a life-saving need.

Aiming to introduce manufacturing capability into GSK’s Parma site for Fostemsavir (a life-saving HIV drug for patients with limited or no other treatment options available), this project’s brief was ambitious.. To maintain supply while the drug was in development and clinical trials, GSK had to build and commission a brand new facility in a shorter timeframe than had ever been achieved before.. As lead designer, Bryden Wood formed a collaborative team with external partners and client representatives to capture functional requirements in “Chip” models that could be rapidly configured to allow many design options to be evaluated in a short time..The ability to undertake rapid digital optioneering was particularly important as forecast demand volumes were uncertain and clinical manufacturing requirements for the drug were still being developed during the design phase.We developed a capacity model in-house to inform decisions around unit operations and scale..

The final design concept was deliberately simple.Process spaces were housed on a single level, raised above the ground to meet flood protection requirements.

A technical floor was located above the process.

Offsite modular prefabrication helped improve programme delivery..How large processes need large peak demands of inputs, how many design factors are not linear so doubling the size of a process can mean 4x or 8x the energy, the time, or the effort.

For some processes, a colony of ants would be much more efficient than a brontosaurus..The point is that scale is a complex but critical issue if you are concerned with multiple factors – profitability, economic agility, sustainability, system reliability.

We cannot just keep doing what we have always done or following over-simplistic thinking.The technological advances of the last 50 years have allowed us to be able to model scenarios from millisecond by millisecond to decade by decade.